Healthy Lifestyle and Leukocyte Telomere Length in U.S. Women
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منابع مشابه
Healthy Lifestyle and Leukocyte Telomere Length in U.S. Women
CONTEXT Whether a healthy lifestyle may be associated with longer telomere length is largely unknown. OBJECTIVES To examine healthy lifestyle practices, which are primary prevention measures against major age-related chronic diseases, in relation to leukocyte telomere length. DESIGN AND SETTING Cross-sectional analysis in the Nurses' Health Study (NHS). PARTICIPANTS The population consist...
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BACKGROUND Age-related cognitive decline begins in mid-life and continues with advancing age. Leukocyte telomere length (LTL) shortens with age, and inflammation and oxidative stress enhance this process. Shorter LTL is associated with dementia. METHODS The relationship between cognitive function and LTL was investigated in a cross-sectional study of 382 women (mean age 50.6 years, range 19-7...
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In culture, replicating human somatic cells display progressive telomere shortening. Ultimately, such cells either undergo apoptosis or enter a state of replicative senescence that is triggered by critically shortened telomeres. Accordingly, telomere length is an index of both the replicative history and the replicative potential of human somatic cells in culture (1). Most replicating human som...
متن کاملHomocysteine levels and leukocyte telomere length.
OBJECTIVE Elevated plasma homocysteine is a risk factor for vascular diseases, possibly due to homocysteine-mediated increase in oxidative stress and inflammation. As leukocyte telomere length (LTL) registers the cumulative oxidative stress and inflammation, we examined the relationship between homocysteine and LTL. METHODS LTL was measured using the Southern blot method. The relationship bet...
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PURPOSE Birdshot Uveitis (BU) is an archetypical chronic inflammatory eye disease, with poor visual prognosis, that provides an excellent model for studying chronic inflammation. BU typically affects patients in the fifth decade of life. This suggests that it may represent an age-related chronic inflammatory disease, which has been linked to increased erosion of telomere length of leukocytes. ...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0038374